Scientist page is loaded## Scientistlocations: Ireland - Dublin - Grange Castletime type: 全职posted on: 今天发布job requisition id: 4946403**Background:**The technical services team are seeking an experienced process scientist whose role will focus on supporting upstream and downstream commercial manufacturing and technology transfers to the small scale flex (SSF) manufacturing facility. This role will be located at the Pfizer Grange Castle site. The SSF facility is a multiproduct manufacturing area specialising in the manufacture of therapeutic proteins derived from mammalian cell culture for a range of clinical and commercial products.This position will be an integral part of a high performing technical services team whose role will involve:* Support commercial manufacturing to meet commercial requirements including investigations, process robustness and process improvements* Scale up of mammalian cell culture and purification processes from bench and pilot scale and support technology transfers to the facility* Perform, present and execute facility fits, mass balance generation, equipment sizing, gap assessments and mitigation of operational challenges foreseen to ensure an equivalent process is transferred to Grange Castle* Provide independent decision making for strategic input into facility and equipment design* Prepare, review & execute technology transfer protocols, supporting documentation and at scale process trials to deliver an efficient technology transfer* Author and review responsible sections of regulatory dossiers including health authority query responses* Partners with the management and technical team to identify best practices, technology transfer efficiencies and optimisations during transfer.* Develops and maintains effective working relationships with other division groups supporting technology transfers, validation and process support.**Requirements**:* Minimum of 3 - 6 years of mammalian cell culture and/ or purification process development/ late-stage characterisation and technology transfer/ technical services experience in stainless steel and/or single use facilities* Demonstrated history and in-depth knowledge of cell culture and/ or purification scale up practices, technology transfer, facility fit, equipment sizing and mass balance generation for clinical/ commercial manufacture* Knowledge and experience of process validation strategies, studies and requirements* Knowledge of regulatory submissions and response of queries from health authorities* In depth knowledge of cGMP regulatory requirements related to the design and control of drug substance processes**Skills**:* High technical capability, interpret complex data, problem solving and technical learning.* Promote information sharing and excellent interpersonal skills* Capability of working in a multi-disciplinary team environment to tight timelines* Effective communication, planning and organisation skills to deliver documentation. Work Location Assignment: Hybrid **Additional Information*** In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.* Please note there is no relocation support available for this position**How to apply*** Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you!Purpose**Breakthroughs that change patients' lives**... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.Digital Transformation StrategyOne bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.Equal Employment OpportunityWe believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability InclusionOur mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!Engineering #J-18808-Ljbffr
A global biopharmaceutical company is seeking an experienced Scientist to join their technical services team in Dublin. This role involves supporting both upstream and downstream manufacturing processes and ensuring efficient technology transfers. The ideal candidate must possess 3-6 years of experience in mammalian cell culture and purification process development. You will author regulatory documentation and collaborate with various divisions to enhance manufacturing practices. This position offers a hybrid work model and is integral to achieving high-quality standards in drug production. #J-18808-Ljbffr
A global pharmaceutical company in Dublin is seeking an experienced process scientist for their Grange Castle site. The role supports commercial manufacturing and technology transfers in a multiproduct facility focused on therapeutic proteins. Ideal candidates will have 3-6 years of experience in mammalian cell culture and purification processes, demonstrating strong problem-solving skills and knowledge of cGMP requirements. This role offers a hybrid work environment with no relocation support available. #J-18808-Ljbffr
Use Your Power for Purpose Our breakthroughs would not reach the hands of patients without our dedicated pharmaceutical manufacturing team. We rely on agile members who understand the critical impact of their role in Pfizer’s mission. Patients need colleagues like you who take pride in their work and continuously strive to improve outcomes. Your efforts ensure that patients and physicians have timely access to the medicines they need. What You’ll Do Lead with Expertise: Own and resolve complex technical issues, lead deviation investigations, and implement effective CAPAs that ensure robust, compliant manufacturing. Be the Go‑To SME: Provide deep technical insight into upstream and downstream processes, supporting troubleshooting, training, and process optimisation. Drive Innovation: Identify and lead process and equipment improvements, from concept through to funding and implementation. Collaborate Cross‑Functionally: Work closely with Operations, MSAT, Quality, Engineering, and Technical Services to ensure seamless execution and continuous improvement. Project Leadership: Manage short‑duration technical projects, ensuring delivery on scope, cost, and schedule while navigating technical challenges. Champion Excellence: Promote a culture of Right‑First‑Time and Zero Defects, and contribute to audit readiness and defence as a technical expert. Mentor and Influence: Coach peers and junior colleagues, sharing best practices and fostering a culture of learning and collaboration. What You Bring A degree in Science or Engineering (Chemical/Biological focus preferred); equivalent experience considered. 5+ years of cGMP experience in biopharma manufacturing, technical operations, or engineering. Strong working knowledge of upstream cell culture and downstream purification. Proficiency with digital tools such as eQMS (Veeva Vault/QTS), MCS, PI, LIMS, and AMPS. Demonstrated ability to work independently, lead investigations, and influence cross‑functional teams. Method One certification and experience with process monitoring systems and automated control systems. Excellent communication, problem‑solving, and stakeholder engagement skills. What Sets You Apart You’re not just technically strong — you’re a strategic thinker who sees the bigger picture. You’re proactive, solutions‑focused, and thrive on driving improvements that matter. You’re a natural collaborator who builds trust and delivers results across functions and levels. Our Culture We value curiosity, courage, and collaboration. You’ll be supported by a team that shares knowledge, celebrates success, and is committed to continuous learning and development. We invest in our people through 70:20:10 development planning, lean capability building, and meaningful career progression. What We Offer: or Why Choose Pfizer Competitive Salary Annual Bonus and Share Schemes Pension Scheme Long term Income Protection Healthcare for you and your family Career development opportunities Health and wellbeing initiatives Subsidised Canteen Onsite Gym and Saloon Sports and social club (Swim Society, Women’s Mentoring programme, Pfizer Pride & many more) Working Patterns and Duration Day based Monday to Friday. Work Location Assignment: Flexible. Work Location Assignment: Hybrid. Closing Date: Friday 16 January 2025. Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How To Apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! Purpose Breakthroughs that change patients’ lives. At Pfizer we are a patient‑centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company‑wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability Inclusion Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here! #J-18808-Ljbffr
A global biopharmaceutical leader is seeking an experienced Scientist for their Dublin facility. This role focuses on supporting both upstream and downstream commercial manufacturing as well as overseeing technology transfers. Candidates should have a solid background in mammalian cell culture and purification processes, along with strong skills in regulatory compliance. This position emphasizes teamwork and offers a hybrid work environment designed to meet the needs of its members. #J-18808-Ljbffr
A leading pharmaceutical company in Dublin is looking for a Process Scientist to support upstream and downstream commercial manufacturing. The candidate will have 3-6 years of experience in mammalian cell culture and purification processes. This role involves supporting technology transfers, enhancing production processes, and ensuring compliance with regulatory requirements. The position offers a hybrid work model and is integral to a high-performing technical services team. #J-18808-Ljbffr
A global pharmaceutical leader seeks a technical expert to resolve complex issues in Dublin. You will lead projects and improve manufacturing processes while collaborating across teams. Ideal candidates have a degree in Science or Engineering and over 5 years of experience in biopharma manufacturing. This role offers a competitive salary, annual bonus, and comprehensive benefits within a hybrid work environment. #J-18808-Ljbffr
Scientist page is loaded## Scientistlocations: Ireland - Dublin - Grange Castletime type: Vollzeitposted on: Heute ausgeschriebenjob requisition id: 4946403**Background:**The technical services team are seeking an experienced process scientist whose role will focus on supporting upstream and downstream commercial manufacturing and technology transfers to the small scale flex (SSF) manufacturing facility. This role will be located at the Pfizer Grange Castle site. The SSF facility is a multiproduct manufacturing area specialising in the manufacture of therapeutic proteins derived from mammalian cell culture for a range of clinical and commercial products.This position will be an integral part of a high performing technical services team whose role will involve:* Support commercial manufacturing to meet commercial requirements including investigations, process robustness and process improvements* Scale up of mammalian cell culture and purification processes from bench and pilot scale and support technology transfers to the facility* Perform, present and execute facility fits, mass balance generation, equipment sizing, gap assessments and mitigation of operational challenges foreseen to ensure an equivalent process is transferred to Grange Castle* Provide independent decision making for strategic input into facility and equipment design* Prepare, review & execute technology transfer protocols, supporting documentation and at scale process trials to deliver an efficient technology transfer* Author and review responsible sections of regulatory dossiers including health authority query responses* Partners with the management and technical team to identify best practices, technology transfer efficiencies and optimisations during transfer.* Develops and maintains effective working relationships with other division groups supporting technology transfers, validation and process support.**Requirements**:* Minimum of 3 - 6 years of mammalian cell culture and/ or purification process development/ late-stage characterisation and technology transfer/ technical services experience in stainless steel and/or single use facilities* Demonstrated history and in-depth knowledge of cell culture and/ or purification scale up practices, technology transfer, facility fit, equipment sizing and mass balance generation for clinical/ commercial manufacture* Knowledge and experience of process validation strategies, studies and requirements* Knowledge of regulatory submissions and response of queries from health authorities* In depth knowledge of cGMP regulatory requirements related to the design and control of drug substance processes**Skills**:* High technical capability, interpret complex data, problem solving and technical learning.* Promote information sharing and excellent interpersonal skills* Capability of working in a multi-disciplinary team environment to tight timelines* Effective communication, planning and organisation skills to deliver documentation. Work Location Assignment: Hybrid **Additional Information*** In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.* Please note there is no relocation support available for this position**How to apply*** Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you!Purpose**Breakthroughs that change patients' lives**... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.Digital Transformation StrategyOne bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.Equal Employment OpportunityWe believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability InclusionOur mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!Engineering #J-18808-Ljbffr
A leading pharmaceutical company in Dublin is seeking an experienced Automation Engineer to join their Automation team. This role involves collaborating with various stakeholders to ensure effective implementation of automation strategies in a highly regulated environment. Candidates should possess a degree in Engineering and at least 5 years of experience in automation within the biotechnology industry. This is an on-premise position offering the opportunity to contribute to meaningful advancements in healthcare. #J-18808-Ljbffr
Automation Engineer page is loaded## Automation Engineerlocations: Ireland - Dublin - Grange Castletime type: Full timeposted on: Posted Todayjob requisition id: 4947963Job Title: Automation Engineer (DS2) Department: Automation Engineering**Role Description:**Pfizer Ireland Pharmaceuticals' Grange Castle manufacturing plant is situated on a 90-acre site in South Dublin. The state-of-the-art technology and production expertise at Grange Castle result in the production of quality-driven products that improve people's lives around the world. The site houses advanced pilot plants, laboratories, and equipment for developing processes for producing various biological drugs, including proteins.The experienced Automation Engineer will be part of the Grange Castle Drug Substance 2 Automation team, working in our brand new highly automated plant at Grange Castle.Reporting to the Automation Lead, this role will be a key member of the DS2 Automation team through commissioning, qualification, demo batches, and supporting the ultimate transition through to sustaining manufacturing.**Some Role Responsibilities:*** Working as part of an experienced Automation DS2 Team.* Collaborating with Process SMEs, CQV Leads, and Automation Engineers to understand process requirements.* Generating all the key technical inputs into functional design specifications from all stakeholders.* Participating in and signing off on key Functional design aspects as required.* Implementing the ACP’s (Automation Change Pack) to make the required code changes.* Supporting project reviews internally with key stakeholders within Automation and customers as required.* Supporting commissioning activities, qualification activities, and the transition from project to sustaining manufacturing.* Ensure that work performed is accurate, timely, efficient and compliant with corporate policies, Good Manufacturing Practices regulations, and Regulatory Agency requirements.* Must be solutions orientated, delivery focused and passionate about supporting production with technical support solutions.**Qualifications:**Must-Have:* Degree in Electrical/Electronic or Chemical Engineering, or a related field with substantial experience.* 5+ years of experience as an Automation Engineer within the biotechnology industry in a regulated GMP environment, delivering Emerson DeltaV solutions (S88 model) and/or high-level expertise in PLC and SCADA based systems including integration.* Ability to liaise with process engineers to define scope and deliver on specifications with very strong documentation skills and attention to detail.* Automation Compliance lifecycle & Change management relevant experience* Experience with process plant commissioning.* Strong team player with the ability to develop relationships and work closely with several cross-functional disciplines, both within and outside of the function and organization.* Good working knowledge of ISA95 and ISA88, CFR (Code of Federal Regulation) Part 11, EU (European Union) Annex 11.* Excellent communication skills with the ability to formulate thoughts in a clear and concise manner to provide clarity and a path forward on any issues.Nice-to-Have:* Master's degree* Knowledge of site operations Work Location Assignment: On Premise **Additional Information*** In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland.* Please note there is no relocation support available for this position**How to apply*** Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you!Purpose**Breakthroughs that change patients' lives**... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.Digital Transformation StrategyOne bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.Equal Employment OpportunityWe believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability InclusionOur mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here!EngineeringPfizer careers are like no other. In our culture of individual ownership, we believe in our ability to improve future healthcare, and potential to transform millions of lives. We’re looking for new talent to join our global community, to unearth new innovative therapies that make the world a healthier place. #J-18808-Ljbffr
