Job Summary: Analytical Scientist for Analytical Research & Development at Pfizer Pfizer's purpose is to deliver breakthroughs that change patients' lives. As an Analytical Scientist, you will play a key role in accelerating and bringing the best-in-class medicines to patients around the world. Key Responsibilities: Perform laboratory work in support of analytical testing of pharmaceutical projects, including chromatography, KF, spectroscopy, or mass spectrometry. Develop analytical methods, test and release raw materials and intermediates to support pharmaceutical development efforts. Support in-process control (IPC) for plant operations, method development and testing, and method transfers to and from the RCMF facility. Develop, verify and validate analytical methods across a range of techniques (HPLC, UPLC, GC, UV, KF, IR, SFC, MS). Review and verify scientific experiments and data documented in electronic laboratory notebooks. Provide analytical support for Process Analytical Technology (PAT) in the lab and for manufacturing for batch and continuous processes. Requirements: PhD in analytical chemistry with 0+ years' experience in the pharmaceutical industry, ideally within an analytical development role. Or BSc/MSc in a degree with significant analytical focus and up to 2+ years' experience in the pharmaceutical industry, ideally within an analytical development or GMP role. Desirable Skills: Experience in the use of general analytical techniques (HPLC, GC, KF, IR, LC-MS, UV). Ability to meet project milestones under general supervision, plan and manage priorities for specific projects. Experience in problem-solving skills and instrument troubleshooting. Demonstrated oral and written communication skills, including visualization of data and drafting reports. Relevant analytical development and/or GMP experience. About Pfizer: Pfizer is a global biopharmaceutical company that applies science and technology to deliver innovative therapies that extend and improve lives.
Pfizer seeks an Analytical Scientist to support drug development in the Clinical Manufacturing Facility, Cork, by applying analytical methodologies to characterize pharmaceutical substances and products. Key Responsibilities: Perform laboratory work in support of analytical testing of pharmaceutical projects using chromatography, spectroscopy, and mass spectrometry. Develop analytical methods, test and release raw materials and intermediates, and document experimental results. Support in-process control for plant operations, method development and testing, and method transfers. Develop, verify, and validate analytical methods across various techniques. Review and verify scientific experiments and data, and provide analytical support for Process Analytical Technology (PAT). Interact with project team members, present data, and review critical data and reports. Requirements: PhD in analytical chemistry with 0+ years' experience in the pharmaceutical industry, or BSc/MSc with significant analytical focus and up to 2+ years' experience. Experience in general analytical techniques, problem-solving skills, and instrument troubleshooting. Demonstrated oral and written communication skills, including data visualization and report drafting. Relevant analytical development and/or GMP experience, and experience with software and information systems. Nice-to-Have: Experience in analytical method transfers, method development, and GMP laboratory experience. Knowledgeable in vibrational spectroscopy and Process Analytics (PAT) experience. Additional Information: Legally eligible to work in Ireland. No relocation support available for this position.
Pfizer are currently recruiting for a Process Safety Engineer based in the EHS Department of the Ringaskiddy API Plant. This position will report directly to the Process Safety and Occupational Hygiene Team Leader and will be supporting elements of Process Safety onsite. Main Areas of Responsibility The Ringaskiddy site is an Upper Tier COMAH site so the role will support the process safety management system as required by the COMAH Safety Report as follows: Chair and document process and equipment Hazop assessments and other process safety related risk assessments; Oversee introduction of new products to the site from a process safety perspective; Responsible for process safety elements associated with running product campaign(s) on plant and ensuring that all processes are managed effectively; To propose, develop and implement improvements and modifications from a process safety perspective to process areas and equipment in order to improve operations; Ensure compliance with relevant site, corporate and industrial standards; Interact with change control system and approve from an EHS perspective; Trouble shoot related process safety issues; Review and approval of process safety related documentation, for example process HAZOPs and Capital Project Lifecycle system requirements; Provide relevant training to colleagues, where required; Support safety investigations throughout the site; Conduct safety audits and continuously improve the Site safety management systems. Qualifications The successful candidates will: Preferably be educated to honours degree level (or higher) in Chemical Engineering, Chemistry or other related discipline and ideally have 3 to 4 years relevant experience within in the pharmaceutical industry. Some experience in process safety subject matters such as ATEX, COMAH and reaction chemistry hazards would be beneficial; A good understanding of process safety and process engineering, including general processing and plant operations is essential. In addition, candidates will be highly motivated and able to demonstrate strong interpersonal and communication skills, as well as possessing problem solving and decision making abilities. Role Perks The role offers a hybrid model of work from home and on site: Some flexibility in working hours Opportunity to be part of a dynamic company that encourages and supports personal development Role also offers good networking opportunities both within locality and Global Pfizer network Ringaskiddy site is critical to the Pfizer mission statement of “Breakthroughs that change patients lives”. This role is an integral part to the success of that mission Pfizer Behaviours/Core Competencies Acts Decisively, Change Agile, Seizes Accountability, Self-Awareness, Grows Self, Commits to "One Pfizer", Builds Peer relationships Work Location Assignment Hybrid Application Closing Date 24-OCT-2024 Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to Apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! Purpose Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability Inclusion Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here! #J-18808-Ljbffr
Senior Associate, Cloud Security Engineer AI ROLE SUMMARY The Cloud and Network Security Services team represents the Digital Center of Excellence (CoE) for cloud infrastructure capabilities, providing foundational public and private cloud services to all business lines, globally across Pfizer. Cloud and Network Security Services is a high-performing team, focused on delivering secure, scalable, compliant, operationally viable, and cost-effective cloud solutions. Working within Cloud and Network Security Services is to be at the cutting edge of cloud technology within the context of the world’s leading biopharmaceutical organization, at a time when adoption of these technologies is increasing rapidly. As a Senior Associate, AI Cloud Security Engineer, you will play a pivotal role in safeguarding Pfizer’s systems and data. Your deep expertise in cybersecurity and AI cloud security will be instrumental in identifying potential vulnerabilities, developing robust security protocols, and responding to security incidents. You will work closely with various teams to integrate security measures into our technology infrastructure and promote a culture of security awareness across the organization. Your role will involve staying abreast of the latest cybersecurity threats and trends, ensuring our security strategies and practices are up-to-date and effective. Your leadership and technical skills will be crucial in strengthening our security posture and protecting our organization from cyber threats. ROLE RESPONSIBILITIES Identify potential vulnerabilities in AI cloud environments and develop robust security protocols. Respond to security incidents and work closely with various teams to integrate security measures into our technology infrastructure. Security Protocols Development: Develop and implement robust security protocols to protect the organization's systems and data from potential threats. Vulnerability Assessment: Conduct regular vulnerability assessments and penetration testing to identify potential weaknesses and implement necessary security measures. Stay abreast of the latest cybersecurity threats and trends in Generative AI, LLM, and Fine-tune model. Security Integration: Collaborate with various teams to integrate security measures into the technology infrastructure, ensuring security is considered at all stages of development and deployment. Security Awareness: Promote a culture of security awareness across the organization, providing training and guidance to staff on best practices in cybersecurity. Threat Intelligence: Stay abreast of the latest cybersecurity threats and trends, ensuring the organization's security strategies and practices are up-to-date and effective. Compliance: Ensure compliance with relevant security standards and regulatory requirements, conducting regular audits and making necessary adjustments to security protocols. BASIC QUALIFICATIONS Bachelor’s degree in computer science, Engineering, a related field or equivalent experience. 3+ years’ experience developing and/or maintaining cloud security controls. Knowledge of public and private cloud platforms (AWS, Azure, or Google Cloud). Knowledge and experience in Artificial intelligence security controls. Experience in developing native cloud security controls such as Azure policy definitions, AWS service control Policy. Proficiency in at least one programming language, such as Python, Java, or Go. Experience in Cloud Security Products such as Wiz, AWS Security Hub, and Azure Defender. Excellent problem-solving skills, strategic thinking, and strong business acumen. Excellent communication skills, both written and verbal, with the ability to present complex technical information in a clear and concise manner. Demonstrated ability to work in an agile work environment possessing qualities such as a collaborative mindset, adaptability to change, and a proactive problem-solving approach. PREFERRED QUALIFICATIONS Certifications in cybersecurity, such as Certified Information Systems Security Professional (CISSP) or Cloud Specific Certifications (i.e., AWS cloud practitioner, Azure AZ-900). Experience with cloud security and understanding of relevant technologies and practices. Familiarity with regulatory standards such as GDPR, ISO 27001, or HIPAA. Experience in a leadership role, with the ability to guide and mentor junior security engineers. Demonstrated ability to stay current with the latest developments in cybersecurity threats and trends. Experience with security in DevOps and Agile environments. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Respond on short notice during normal working hours. Extended hours, weekends, and holidays may occasionally be required during critical events. Limited travel may be required. How to apply Make a difference today! All suitable candidates should apply through the link with CV provided. We are looking forward to hearing from you! In order to be considered for this position you need to be legally eligible to work in the EU. Pfizer is an equal opportunity employer and complies with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. Due to the high volume of applications we will be contacting successful candidates only. #J-18808-Ljbffr
Pfizer are currently recruiting for a Process Safety Engineer based in the EHS Department of the Ringaskiddy API Plant. This position will report directly to the Process Safety and Occupational Hygiene Team Leader and will be supporting elements of Process Safety onsite. Main Areas of Responsibility The Ringaskiddy site is an Upper Tier COMAH site so the role will support the process safety management system as required by the COMAH Safety Report as follows: Chair and document process and equipment Hazop assessments and other process safety related risk assessments; Oversee introduction of new products to the site from a process safety perspective; Responsible for process safety elements associated with running product campaign(s) on plant and ensuring that all processes are managed effectively; To propose, develop and implement improvements and modifications from a process safety perspective to process areas and equipment in order to improve operations; Ensure compliance with relevant site, corporate and industrial standards; Interact with change control system and approve from an EHS perspective; Trouble shoot related process safety issues; Review and approval of process safety related documentation, for example process HAZOPs and Capital Project Lifecycle system requirements; Provide relevant training to colleagues, where required; Support safety investigations throughout the site; Conduct safety audits and continuously improve the Site safety management systems. Qualifications The successful candidates will: Preferably be educated to honours degree level (or higher) in Chemical Engineering, Chemistry or other related discipline and ideally have 3 to 4 years relevant experience within in the pharmaceutical industry. Some experience in process safety subject matters such as ATEX, COMAH and reaction chemistry hazards would be beneficial; A good understanding of process safety and process engineering, including general processing and plant operations is essential. In addition, candidates will be highly motivated and able to demonstrate strong interpersonal and communication skills, as well as possessing problem solving and decision making abilities. The role offers a hybrid model of work from home and on site: Some flexibility in working hours; Opportunity to be part of a dynamic company that encourages and supports personal development; Role also offers good networking opportunities both within locality and Global Pfizer network; Ringaskiddy site is critical to the Pfizer mission statement of “Breakthroughs that change patients lives”. This role is an integral part to the success of that mission. Pfizer Behaviours/Core Competencies. Acts Decisively, Change Agile, Seizes Accountability, Self-Awareness, Grows Self, Commits to "One Pfizer", Builds Peer relationships. Work Location Assignment: Hybrid. Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! #J-18808-Ljbffr
Analytical Scientist for Analytical Research & Development at the Ringaskiddy Clinical Manufacturing Facility, Cork Why Patients Need You Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. In Analytical Research & Development you will apply innovative measurement science, data analytics and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world. What You Will Achieve As a Scientist in Analytical Research and Development, you will take an active role in supporting drug development by applying a variety of analytical methodologies to support physical and chemical characterization of drug substances (including raw materials and intermediates). You will have working knowledge and ability to operate analytical techniques such as chromatography and spectroscopy used for the characterization of pharmaceutical substances and products is desired. You will also be involved in method transfer activities in and out of the RCMF analytical lab. At the RCMF you will be involved in the manufacturing support for clinical material at various stages of clinical development as well as supporting chemistry and analytical method development. Responsibilities Perform laboratory work in support of analytical testing of pharmaceutical projects with some experience in any of the following analytical methodologies: chromatography, KF, spectroscopy or mass spectrometry. Responsibilities may include developing analytical methods, testing and release of raw materials and intermediates to support pharmaceutical development efforts, and documentation of experimental results. In-process control (IPC) support for plant operations. Method Development and testing to support cleaning of production facility. Involvement in methods transfers to and from the RCMF facility. Development, Verification and Validation of analytical methods across a range of techniques (HPLC, UPLC, GC, UV, KF, IR, SFC, MS). Review and verify scientific experiments and data documented in electronic laboratory notebooks. Provide analytical support for Process Analytical Technology (PAT) in the lab and for manufacturing for batch and continuous processes across a range of techniques such as Mid-IR, UV, FBRM, Online LC. Effectively interact with project team members for various tasks including presentation of data and critical review of data and preparation of technical reports. Demonstrate proficiency with a wide variety of software and information systems. The colleague must be able to interact effectively with peers and leaders as part of a multi-disciplinary team and thrive in a fast-paced environment. Education and Experience A PhD in analytical chemistry ideally combined with 0+ years’ experience in the pharmaceutical industry, ideally within an analytical development role; or A BSc/MSc in a degree with significant analytical focus and ideally up to 2+ years’ experience in the pharmaceutical industry, ideally within an analytical development or GMP role. Qualifications Must-Have Experience in the use of general analytical techniques e.g HPLC, GC, KF, IR, LC-MS and UV. Ability to meet project milestones under general supervision, plan and manage priorities for specific projects. Experience in problem-solving skills and instrument troubleshooting. Demonstrated oral and written communication skills, including visualization of data and drafting reports. Relevant analytical development and/or GMP experience. Experience with a wide variety of software and information systems (e.g. electronic lab notebooks, Empower and LIMS). Ability to work in a team environment in GMP laboratory environment performing experiments. Ability to perform data analysis, record results in electronic lab notebooks and effectively communicate in a team environment. Ability to adhere to safe laboratory practices. Good documentation skills with high attention to detail, strong organizational skills, team oriented, effective interpersonal and communication skills. Nice-to-Have (one or more of the following) Experience in the analytical method transfers. Method development experience. Experience in a GMP laboratory. Knowledgeable in vibrational spectroscopy (NIR, IR, Raman, UV-Vis). Process Analytics (PAT) experience. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Do not anticipate more than 10% travel. Application closing date: 23-oct-2024 Work Location Assignment: Onsite Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! #J-18808-Ljbffr
The Digital Manufacturing Team is responsible for the delivery of Pfizer’s Core Digital Manufacturing Operations Management (MoM) capabilities at every level of the Pfizer Global Supply (PGS) Plant Network (ISA 95 Levels 0-4). These solutions are critical to Manufacturing & Lab Execution, Manufacturing Process Intelligence and Production Optimization that aim to improve product quality, increase asset utilization/uptime, automate manual workflows, and streamline plant floor operations. The Digital Manufacturing mission is to “Drive predictive operations through connected digital experiences to accelerate supply and enable delivery of breakthrough medicines. The Manufacturing 4.0 Team supports all of Pfizer’s Core Manufacturing & Engineering Solutions, while enabling a secure, seamless flow of contextualized data from the device & control levels, all the way to the top of the Enterprise. Our goal is to create persona driven, connected experiences across our shop floors to predict and optimize operations, while providing real-time insights to operators. Come join us to create Pfizer’s Factory of the Future! The Global Historian team is primarily responsible for the management of a global Historian and ensuring data access to site Historians. This team supports sites with data acquisition and interface management. The Historian team is responsible for the maintenance of Pi infrastructure and the system availability and data accuracy. The Global Historian is a core enabler for the Digital Manufacturing portfolio and supports Pfizer’s AI strategy. A key responsibility of this role is to support teams with data availability through the Historian for application development and validation. This role requires clear communication skills with senior stakeholders and very strong organizational skills. The successful applicant will be expected to manage a team of engineers that define global standards and introduce best practice guidelines. ROLE RESPONSIBILITIES The Enterprise Historian Product Manager responsibilities include but are not limited to: Pi System & Infrastructure Maintenance Ensuring data accuracy and validation Vendor Engagement Manage team of Pi Engineers Co-ordinate data availability for consuming systems Define data requirements and work with site automation teams to achieve this. Work on and lead multiple highly complex projects that require a strong understanding of emerging & Next Gen digital technologies. Communicate clearly with customers and stakeholders on the benefits of data availability and digital transformation. Contribute and collate content for Governance and stakeholders. e.g. Governance meetings, Scrum Meetings etc Collaborate with stakeholders and customers to manage roadmaps and deliverable content. Liaise with Digital colleagues and other stakeholders to execute required technical and compliance activities in support of sprint releases. Ensure projects are completed on schedule, within budget and meet technical requirements of the assignment. Ensure continuous improvement of Aveva Historian and other Digital technologies. BASIC QUALIFICATIONS Bachelor’s degree required, major in a technical field such as Information Technology or Life Sciences a plus. 7 years’ experience with Data Infrastructure with at least 5 years’ experience with historians. Strong understanding of Automation Infrastructure. Strong project management experience. Leading and influencing virtual team members in a cross functional team. Experience with Aveva/ Osi PI required. Previous experience in SAFe is preferable. Ability to work in ambiguous situations and synthesize complex information to determine and explain best course of action. Ability to work across multiple concurrent activities and successfully adapt to changing priorities as required. Demonstrated skills in analysis and problem solving. Facilitation, negotiating and presentation skills. Experience in all stages of system and application lifecycle from value analysis, business case development, solution deployment through value realization and system retirement is a significant advantage. A thorough understanding of system GMP requirements and demonstrable knowledge of computer system design and maintenance lifecycle in GMP environments. Strong experience in MS Office Products (i.e. MS Word, Excel, PowerPoint). PREFERRED QUALIFICATIONS OSIsoft PI System Certification. Familiarity with the other PGS Transformation workstreams including IMEx and Manufacturing Technology. Work Location Assignment: Hybrid Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! Purpose Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability Inclusion Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here! #J-18808-Ljbffr
Ringaskiddy API site in Cork plays a critically strategic role within Pfizer, it is the global site for new small molecule API products through scale up and launch, as well as manufacture of large volume patented and off-patent medicines. Colleagues on the site use state of the art equipment and leading-edge technology, as well as work collaboratively with Research and Development to provide the highest quality innovative products to the market. About the Roles We are recruiting for people with a background in Science, Engineering & Technology to become part of our onsite manufacturing team including our new expanding production facility OSP5. We are looking for innovative and passionate people to work across a wide range of disciplines including New Product Introduction, Optimisation of established products and Tech Transfer of products within our plants onsite and across our network in the new State-of-the-Art Production Facility OSP5. This role is ideally suited for people with backgrounds in Science, Engineering & with an ever-increasing focus on utilising the latest technologies to ensure medicines are manufactured to the highest standards in the most efficient way possible. The following is an overview of the role responsibilities: Work at the core of our site as part of a cross functional Process-Centric Team to own the day-to-day manufacturing responsibilities, delivering important therapeutic products in line with customer and patient demands. Demonstrate and implement continuous improvements to deliver optimum and robust chemistry and efficient use of plant equipment under our banner of excellence in Safety, Quality, Cost and Supply. Leverage process and technical knowledge gained on lab-to-plant scale to investigate potential challenges and implement innovative and lasting solutions. Project manage the work in an efficient & structured manner, while easily and effectively communicating with peers and stakeholders. About You Be able to work on your own initiative, be self-driven to set goals and lead a team from within. Have demonstrated problem solving abilities and innovation capabilities. Have excellent interpersonal and communication skills in line with our Pfizer values of Courage, Excellence, Equity and Joy. Hold a Bachelor’s degree (BEng./BSc./MSc./PhD. or equivalent) in a relevant Engineering, Science or Technology discipline. A minimum of 3+ years’ industry (Pharma / Biopharma /Med.Tech.) experience in a comparable role preferred. What We Offer? Permanent position with Competitive Salary plus Bonus Schemes, Healthcare for you and your family, Pension and Share Scheme, Long Term Income Protection and Life Assurance. An on-site role based on our vibrant Ringaskiddy API Campus with the opportunity for flexible working arrangements. Ringaskiddy is close to Cork City and offers onsite gym, health & wellness programs, employee development programs, free parking, subsidized canteen and many more benefits for you to enjoy! Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! Purpose Breakthroughs that change patients' lives ... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability Inclusion Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here! #J-18808-Ljbffr
Ringaskiddy API site in Cork plays a critically strategic role within Pfizer, it is the global site for new small molecule API products through scale up and launch, as well as manufacture of large volume patented and off-patent medicines. Colleagues on the site use state of the art equipment and leading-edge technology, as well as work collaboratively with Research and Development to provide the highest quality innovative products to the market. About the Roles We are recruiting for people with a background in Science, Engineering & Technology to become part of our onsite manufacturing team including our new expanding production facility OSP5. We are looking for innovative and passionate people to work across a wide range of disciplines including New Product Introduction, Optimisation of established products and Tech Transfer of products within our plants onsite and across our network in the new State-of-the-Art Production Facility OSP5. This role is ideally suited for people with backgrounds in Science, Engineering & with an ever-increasing focus on utilising the latest technologies to ensure medicines are manufactured to the highest standards in the most efficient way possible. The following is an overview of the role responsibilities: Work at the core of our site as part of a cross functional Process-Centric Team to own the day-to-day manufacturing responsibilities, delivering important therapeutic products in line with customer and patient demands. Demonstrate and implement continuous improvements to deliver optimum and robust chemistry and efficient use of plant equipment under our banner of excellence in Safety, Quality, Cost and Supply. Leverage process and technical knowledge gained on lab-to-plant scale to investigate potential challenges and implement innovative and lasting solutions. Project manage the work in an efficient & structured manner, while easily and effectively communicating with peers and stakeholders. About You Be able to work on your own initiative, be self-driven to set goals and lead a team from within. Have demonstrated problem solving abilities and innovation capabilities. Have excellent interpersonal and communication skills in line with our Pfizer values of Courage, Excellence, Equity and Joy. Hold a Bachelor’s degree (BEng./BSc./MSc./PhD. or equivalent) in a relevant Engineering, Science or Technology discipline. A minimum of 3+ years’ industry (Pharma / Biopharma /Med.Tech.) experience in a comparable role preferred. What We Offer? Permanent position with Competitive Salary plus Bonus Schemes, Healthcare for you and your family, Pension and Share Scheme, Long Term Income Protection and Life Assurance. An on-site role based on our vibrant Ringaskiddy API Campus with the opportunity for flexible working arrangements. Ringaskiddy is close to Cork City and offers onsite gym, health & wellness programs, employee development programs, free parking, subsidized canteen and many more benefits for you to enjoy! Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position. How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! #J-18808-Ljbffr
Job Description We are seeking a new Senior Manager to help lead Operations & External Development (OED) within Chemical Research and Development (CRD) in Groton, CT, USA. The successful candidate will partner with the Process Chemistry & Technology (PCT) and CRD Management Teams to guide portfolio and operational deliverables, primarily through building and enhancing effective external development partnerships. CRD, as part of Pharmaceutical Sciences Small Molecule (PSSM) within Pfizer Research & Development (PRD), is responsible for the development of process technology for production of Active Pharmaceutical Ingredient (API). CRD leaders engage in all facets of development from small scale synthesis in support of early clinical assessment, to development of robust API processes for commercial scale manufacture. CRD leaders partner with manufacturing specialists in kilo-lab and pilot plant facilities, as well as provide oversight for technology transfer to Pfizer manufacturing sites and third-party facilities. The successful candidate will guide one or more diverse teams of scientists primarily at Chemical Research & Manufacturing Organizations (CDMOs), ensuring clear accountability for, and oversight of, laboratory activities focused on route and process design following the CRD API development workflows. The OED Sr Manager will ensure effective process understanding and transfer of commercial processes to our Pfizer Global Supply (PGS) partners, with accountability for advancement of programs through the API Development Workflows. They will ensure effective resource allocation, portfolio prioritization, development strategy, regulatory documentation, safety, and compliance in the delivery of robust and high-quality processes for APIs through CDMOs. They will ensure effective tracking of, and feedback on, CDMO performance to demonstrate business value and successful progression of projects. They will bring strong knowledge and expertise in Quality by Design and control strategy, including a strong and contemporary working knowledge of ICH guidelines. They will be a proven leader, ensuring effective performance, engagement, and continuous improvement of external development partners. They will be an active member of the PCT Management Team to partner with Engineering, Global External Supply and CRD Manufacturing to ensure smooth operation of the department. They will be accountable for building, communicating and adhering to annual budget targets for externalized API development. The OED Sr Manager serves as a CRD Accountable Manager, assuring overall portfolio progression through effective resource application, with a primary focus on progression of small molecule development assets utilizing a preferred network of CDMOs. Role Responsibilities Critical Thinking Sets goals, objectives, and priorities for the delivery of our portfolio, ensuring effective route and process design to support clinical development, regulatory submission and new product launch. Serves as CRD Accountable Manager to ensure one or more projects progress to agreed milestones, with a primary focus on supporting external development. Provides technical and functional expertise within CRD, ensuring sound process chemistry and Green Chemistry principles are applied to the portfolio, in alignment with ICH guidelines. Leverages technical and functional expertise from PSSM, Medicine Design and PGS to ensure effective development of commercial routes and processes. Considered a subject matter expert in process chemistry, process engineering or analytical research & development. Takes appropriate business risks to achieve desired results, ensuring safety and project delivery at all stages of development. Guides Pfizer and CDMO scientists regarding acceptable levels of risk-taking. Develops solutions to optimize the balance of speed, cost, and quality, integrating CRD technology advances such as computational chemistry, robotics & automation, continuous processing, biocatalysis, chemical synthesis innovation and high throughput screening in the advancement of clinical drug candidates. Ensures effective technical transfer of commercial processes to PGS, including accountability for regulatory submissions, knowledge management, adherence to regulatory guidance and support of regulatory queries. Generates realistic and balanced forecasts for near, mid, and long-term resource needs, and effectively constructs and operationalizes portfolio budgets to ensure efficient, effective advancement of endorsed projects. Leadership Collaborates across PSSM, Medicinal Design and PGS to deliver a cohesive strategy for portfolio delivery through effective use of external resources. Is a CRD Accountable Manager for one or more portfolio programs, ensuring effective portfolio delivery and efficient execution viaa blend of internal and external (CDMO) staff. Manages scientific resources for one or more external development projects, ensuring strong integration of chemistry, analytical and engineering expertise. Adjusts project team size and construct to deliver results while ensuring budgetary targets are met. Uses knowledge of industry, customer requirements and general business environment to adapt and implement strategic actions for the effective delivery of the portfolio via external development partnerships. Develops and exhibits a high level of business knowledge and understanding of CRD Manufacturing and PGS to meet customer requirements for development and manufacturing of small molecule APIs. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact. Communication Actively shares knowledge across CRD, PSSM, Medicine Design and PGS to ensure effective design and execution. Actively engages with industry peers in pre-competitive space to develop and enhance global best practices. Ensures strategic decisions on projects are supported by the CRD Leadership Team (LT). Contributes to the evolution of workflow and best practice with strong collaboration across Co-Development and with clear communication of risks and mitigation strategies to the Portfolio Delivery Team (PDT). Contributes to a communication-rich environment to ensure the knowledge and expertise of the entire team is leveraged. Contributes to the continuous improvement of external API Development Workflows and processes to enhance Co-Development, and regulatory and technical success. Qualifications Required Education/Experience PhD Chemist, Analyst or Chemical Engineer with a minimum of 10 years relevant pharmaceutical research & development experience in small molecule API BSc/MSc Chemist, Analyst or Chemical Engineer with a minimum of 15 years relevant pharmaceutical process research & development experience in small molecule API. Required Technical Skills Recognized as a strong scientific leader within the API process development community. Is acknowledged as an expert in the pharmaceutical development process. Contemporary awareness of significant scientific developments and opportunities in chemistry, analytics and/or chemical engineering. A highly credible technical functional expert with experience in mentoring others. Able to leverage technical and functional expertise across own and related disciplines. Innovative and creative approach to problem solving (both business & scientific), with ability to impact and influence within the global line and outside of the department. Ability to lead in a rapidly changing environment & communicate positive advantages of change. Early adopter of new technologies/ways of working to enhance business productivity. Possesses significant API manufacturing, commercialization, Technology Transfer and Regulatory Dossier authorship and/or review experience. Experience working on large, complex, cross-disciplinary matrix teams. Preferred Technical Skills Expertise in pharmaceutical process development, continuous process development and manufacturing, computational chemistry, biocatalysis and/or high throughput experimentation. Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, oversee and guide the work of others, and create positive business impact. PHYSICAL/MENTAL REQUIREMENTS Ability to perform complex tasks with appropriate mental agility, including mathematical calculations and complex data analysis. High change agility. NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS Will be required to occasionally travel domestically and internationally (5-10%) to support establishment and optimization of CDMO relationships, project team objectives and Co-Development business processes, including API manufacturing campaign preparations. Work Location Assignment:On Premise at an active Pfizer site, with relocation assistance available Additional Information In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. Please note there is no relocation support available for this position How to apply Make a difference today, all suitable candidates should apply with CV below. We are looking forward to hearing from you! Purpose Breakthroughs that change patients' lives ... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. Digital Transformation Strategy One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. Equal Employment Opportunity We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. Disability Inclusion Our mission is unleashing the power of all our people and we are proud to be a disability inclusive employer, ensuring equal employment opportunities for all candidates. We encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments to support your application and future career. Your journey with Pfizer starts here! Research and Development #J-18808-Ljbffr
