Position: Principal Scientist Location: Dublin, Ireland (Hybrid) Contract Duration: 12 Months Lead the science behind life-changing biologics. Own the downstream processes that deliver medicines to patients worldwide. Join a highly technical and collaborative biologics manufacturing team, where your expertise directly impacts product quality, regulatory success, and patient supply. Key Responsibilities Lead troubleshooting and provide technical expertise for downstream GMP biologics manufacturing, including chromatography, ultrafiltration, virus filtration, and virus inactivation. Drive process optimization and continuous improvement initiatives to improve yield, robustness, and cost of goods using data-driven approaches. Act as process subject matter expert for regulatory inspections, audits, and global health authority interactions, including query responses. Represent manufacturing during audits, preparing and defending technical documentation and process decisions. Lead manufacturing investigations, deviation resolution, and implementation of improvements via change control and CAPA. Collaborate cross-functionally with upstream, MS&T, QA, QC, Engineering, and Regulatory teams to support commercial manufacturing. Mentor junior scientists and serve as the senior technical resource within the downstream team. Experience & Qualifications BSc (or equivalent) in a scientific or engineering discipline. 6+ years' experience in drug substance manufacturing technical support within a GMP biologics environment (exceptional candidates with 5 years of strong downstream experience may be considered). Strong technical expertise in downstream processing, including manufacturing troubleshooting and process optimization. Demonstrated knowledge of cGMP compliance and experience supporting regulatory inspections, audits, and global health authority interactions. Proven ability to author, present, and defend technical and scientific approaches in both written and verbal form. Excellent analytical, problem-solving, and communication skills, with the ability to work effectively in cross-functional, matrix organizations. Ability to influence stakeholders without direct authority, balancing product quality, compliance, and operational requirements. Lead, innovate, and make a difference - your expertise in downstream biologics manufacturing will help ensure safe, high-quality medicines reach patients globally. #J-18808-Ljbffr
A leading recruitment firm is seeking a Principal Scientist for a 12-month contract in Dublin, Ireland (Hybrid). In this role, you will lead troubleshooting and provide technical expertise for downstream GMP biologics manufacturing. The ideal candidate has a BSc in a scientific discipline and 6+ years of experience in a GMP biologics environment. Responsibilities include driving process optimization, mentoring junior scientists, and preparing technical documentation for regulatory inspections. This position offers a unique opportunity to impact product quality and patient supply. #J-18808-Ljbffr
Our client is an expanding global pharmaceutical organisation undergoing significant site expansion and transformation at its Cork-based manufacturing facility. As part of this growth, they are seeking an experienced Supply Chain Director to provide strong, visible leadership across end-to-end supply chain operations. This is a senior site leadership role with full accountability for supply chain strategy, execution, and team development within a highly regulated manufacturing environment. The Role You will lead all site supply chain activities, ensuring robust planning, execution, and delivery while supporting ongoing scale-up and transformation. Working closely with manufacturing, quality, engineering, and commercial stakeholders, you will play a key role in improving rigour, predictability, and performance across the operation. Key responsibilities include: Full ownership of end-to-end site supply chain , including planning, logistics, warehousing, distribution, and import/export activities Defining and implementing best-practice supply chain processes , aligned with group standards and local operational needs Leading supply chain transformation initiatives to support capacity expansion, efficiency, and service performance Driving strong cross-functional collaboration to resolve complex operational challenges Setting and managing inventory targets, KPIs, and budgets , ensuring operational and regulatory compliance Acting as a trusted supply chain expert, providing guidance on governance, compliance, and continuous improvement Leading, coaching, and developing supply chain teams , building capability, engagement, and succession within the function About You You will be an experienced supply chain leader with a strong track record in manufacturing-led environments and a clear people-first leadership style. Key requirements include: Senior supply chain leadership experience within Pharmaceutical, FMCG or Medical Device manufacturing environments Proven capability across end-to-end supply chain processes , including planning, logistics, warehousing, and distribution Demonstrated experience leading teams through change, growth, or site transformation Strong people management skills, with clear evidence of team development and organisational build-out Solid understanding of GMP and regulated manufacturing environments The Next Step for you: Should this position be of interest to you please forward your CV to Sarah Mac Mullan from Next Generation Recruitment or alternatively call on the main line on 00 353 1 6498546 Next Generation are specialists in Supply Chain, Procurement, Engineering, Quality, Technical and Operation (permanent, contract and temporary) positions. Applications are in strict confidence. Next Generation will never share your data outside of our organisation without your prior written consent. Please read our Data Protection Policy on our website. By submitting your details you agree to our Tnc #J-18808-Ljbffr
A global pharmaceutical organization in Cork is seeking a Supply Chain Director. This senior site leadership role entails full accountability for supply chain strategy and execution within a regulated environment. The successful candidate will lead site activities, manage inventory and performance metrics, and drive cross-functional collaboration to overcome challenges. Ideal candidates will have extensive experience in supply chain leadership within pharmaceutical or FMCG sectors, with a proven track record in team development and operational excellence. #J-18808-Ljbffr
