CAI is looking for a Senior COHE / LOTO Engineer in Limerick to support a large-scale biopharma commissioning project. This role focuses on the development and management of Control of Hazardous Energy (COHE) and Lockout/Tagout (LOTO) systems across a complex facility. Key responsibilities include hazardous energy assessment, COHE plan development, and ensuring compliance with safety procedures. Candidates should possess 10+ years of relevant experience, a degree in a related discipline, and strong engagement skills. This is a site-based position with a flexible workweek. #J-18808-Ljbffr
Job Title Senior COHE / LOTO Engineer Location Limerick Contract Type Staff or Contract Job Summary We are seeking an experienced COHE / LOTO Coordinator to support a large-scale biopharma commissioning project. This role will be responsible for the development, implementation, and management of Control of Hazardous Energy (COHE) and Lockout/Tagout (LOTO) systems across a complex, multi-system facility during commissioning and start-up activities. The project involves the safe energisation and commissioning of upstream and downstream bioprocessing systems, including bioreactors, CIP/SIP systems, chromatography, filtration, and associated utilities. This includes ensuring all hazardous energy sources are accurately identified, controlled, and managed throughout construction, commissioning, and qualification phases to support safe and compliant system start‑up. This is a highly safety‑critical, site‑based role requiring strong technical expertise, excellent coordination skills, and the ability to operate effectively in a fast‑paced, multi‑contractor commissioning environment. It is ideally suited to experienced professionals with a proven track record in implementing COHE/LOTO programmes within regulated biopharma or pharmaceutical facilities. Key Responsibilities Develop comprehensive COHE plans for all in‑scope equipment prior to and during commissioning activities. Identify, assess, and document hazardous energy sources including electrical, mechanical, hydraulic, pneumatic, chemical, and thermal systems. Conduct field verification of all LOTO procedures to ensure accuracy, compliance, and site applicability. Maintain and manage all LOTO devices, tags, hasps, and lockout kits across the facility. Support commissioning and start‑up teams to ensure strict adherence to hazardous energy control procedures at all times. Coordinate COHE/LOTO requirements with the main contractor, Emerson Automation, vendor teams, and Utilities. Serve as the site SME for hazardous energy control, providing technical guidance and oversight to all personnel. Maintain up‑to‑date COHE documentation aligned with site EHS requirements and the Permit to Work system. Support risk assessments and updates to COHE documentation in line with evolving system configurations during commissioning. Ensure all activities are executed in compliance with applicable safety legislation and site‑specific procedures. Qualifications Degree in Engineering, Biotechnology, Pharmaceutical Sciences, or related discipline. 10+ years’ experience in Commissioning & Qualification / CQV / Validation. Strong working knowledge of GMP requirements, FDA and EMA regulations. Strong hands‑on upstream and downstream bioprocess knowledge. Extensive experience working with Bioreactors, Filtration and concentration systems. Excellent documentation, communication, and stakeholder engagement skills. Other Requirements This is a site‑based role. Must be able to commit to a minimum 40‑hour work week, with flexibility based on project needs. Willingness to travel within Ireland and internationally, if required. Eligible to work full‑time in Ireland. Company Overview CAI is a professional services company established in 1996 that has grown year over year to nearly 800 people worldwide. For Life Sciences and Mission Critical industries that need to deliver critical solutions in high‑stakes environments, we provide accelerated operational readiness and unparalleled performance at the highest standard through our rigorous approach, field‑tested processes, and elite expertise developed over 30 years. Our purpose informs everything we do: We exist to be the trusted solution for our clients as they strive to build a better working world and improve the human experience. We are committed to living our Foundational Principles, both professionally and personally: We act with integrity, we serve each other, we serve society, and we work for our future. We believe in relentless dedication to excellence, pushing boundaries and surpassing expectations. From the beginning, we’ve challenged ourselves to do what others wouldn’t. Not just setting industry standards, but redefining them entirely. We are bold in our thinking and creative in our approach, operating at the intersection of wisdom and technology and thriving when they come together with humanity. For us, operational readiness isn’t simply a goal. It’s a way of life, because tomorrow demands that we be at the forefront of today. We do this through tireless effort, precision, efficiency and an unwavering belief that there is always room for advancement. We’re obsessed with how it will be done. #J-18808-Ljbffr
Job Title Senior C&Q Engineer Location Limerick Contract Type Staff or Contract Job Summary We are seeking an experienced C&Q / Shakedown Engineer to support commissioning activities on a large‑scale, high‑profile biopharma project. This role will focus on the hand‑on execution, optimisation, and stabilisation of upstream and downstream bioprocessing systems, working closely with C&Q Leads, Automation, and cross‑functional project teams. The project centres on the commissioning and qualification of bioreactor systems, ranging from small‑scale development units to large commercial‑scale operations, alongside supporting process equipment including CIP/SIP, chromatography, filtration, and buffer systems. The role will involve system setup, shakedown, and performance tuning to ensure equipment operates reliably and meets Good Engineering Practice (GEP) standards prior to qualification. This is a technically demanding, site‑based role requiring strong troubleshooting, coordination, and problem‑solving capabilities. It is ideally suited to senior‑level engineers with proven experience in commissioning complex biopharma systems and driving systems from mechanical completion through to stable operation and handover. Key Responsibilities Act as the Commissioning SME for assigned equipment packages (e.g. Bioreactors, CIP/SIP, Chromatography, Buffer systems), taking ownership from mechanical completion through to handover for qualification. Lead on‑site system setup, shakedown, and performance tuning activities to achieve stable and optimal operation in line with Good Engineering Practice (GEP). Verify system readiness for commissioning, ensuring all associated utilities are correctly flushed, purged, and prepared prior to energisation. Conduct detailed system and vessel inspections (mechanical integrity, hygienic standards, and cleanliness), ensuring alignment between as‑built systems and design specifications. Troubleshoot and resolve complex technical issues, including misalignments, leaks, control instabilities, and equipment or instrumentation faults. Ensure all shakedown and commissioning activities are executed in accordance with GEP requirements and site safety procedures, including COHE/LOTO where applicable. Coordinate closely with Automation Engineers (e.g. DeltaV/PLC) to support interlock testing, I/O verification, and alarm functionality during system start‑up. Interface with Utilities, HVAC, vendors, and construction teams to ensure effective integration and issue resolution across system boundaries. Support commissioning documentation, including test records, punch list management, and system turnover packages to C&Q teams. Provide technical support and guidance to junior engineers and technicians during commissioning and shakedown activities. Support deviation resolution, field changes, and issue tracking to ensure systems are delivered in line with project timelines and quality expectations. Qualifications Degree in Engineering, Biotechnology, Pharmaceutical Sciences, or related discipline 10+ years’ experience in Commissioning & Qualification / CQV / Validation Strong working knowledge of GMP requirements, FDA and EMA regulations Strong hands‑on upstream and downstream bioprocess knowledge Extensive experience working with Bioreactors, Filtration and concentration systems Excellent documentation, communication, and stakeholder engagement skills Other Requirements This is a site‑based role. Must be able to commit to a minimum 40‑hour work week, with flexibility based on project needs. Willingness to travel within Ireland and internationally , if required. Eligible to work full‑time in Ireland. #J-18808-Ljbffr
CAI is seeking a Senior C&Q Engineer in Limerick to support commissioning activities on a high-profile biopharma project. This role will require execution, optimisation, and stabilisation of bioprocessing systems. You will act as the Commissioning SME, leading system setup and performance tuning, supported by a strong background in GMP, FDA/EMA regulations, and substantial bioprocess experience. Must be flexible for travel and commit to a minimum 40-hour work week. #J-18808-Ljbffr
CAI is looking for a Lead C&Q Engineer in Limerick to oversee C&Q activities on a major biopharma project. This role requires an experienced professional with over 10 years in CQV/Validation, possessing strong knowledge of GMP and regulatory requirements. The key responsibilities include leading C&Q activities, ensuring compliance, and mentoring junior engineers. Candidates should hold an engineering degree and be eligible to work in Ireland, with a commitment of 40+ hours per week. #J-18808-Ljbffr
Job Title Lead C&Q Engineer Location Limerick Contract Type Staff or Contract Job Summary We are seeking an experienced Lead Commissioning & Qualification (C&Q) Engineer to play a key leadership role on a large-scale, high-profile biopharma project. This position will be responsible for overseeing C&Q activities across both upstream and downstream bioprocessing systems, working in close collaboration with the on-site C&Q Lead and cross-functional stakeholders. The project focuses on the commissioning and qualification of bioreactor systems, ranging from small-scale development units to large commercial-scale operations, alongside supporting upstream and downstream process equipment. This includes managing system readiness, coordinating execution across multiple vendors and workstreams, and ensuring seamless material flow through filtration and concentration systems delivering high-value product for final drug product manufacturing. This is a high-impact, technically demanding role requiring strong leadership, coordination, and problem-solving capabilities. It is ideally suited to senior C&Q professionals with a proven track record in delivering complex biopharma projects and managing integrated commissioning and qualification programmes. Key Responsibilities Lead and oversee the full lifecycle of Commissioning & Qualification (C&Q) activities across upstream and downstream process systems, in collaboration with the on-site C&Q Lead. Act as the primary escalation point for technical issues, driving timely troubleshooting, resolution, and risk mitigation across all C&Q workstreams. Conduct system walkdowns and readiness reviews to ensure systems meet pre-requisites for IQ commencement. Ensure all C&Q activities are executed in compliance with GEP (pre-GMP) and GMP standards, maintaining inspection readiness at all stages. Develop and manage the overall C&Q resource plan, including phased onboarding and offboarding aligned with project milestones and MC dates. Track and report project progress, including publishing weekly Actual vs Planned updates to project leadership and key stakeholders. Coordinate closely with Automation (including Emerson/DeltaV), vendors, Utilities, QA, and Validation teams to ensure integrated project delivery. Oversee execution and review of C&Q documentation, including Commissioning Plans, SIAs, Risk Assessments (FMEA), IQ/OQ/PQ protocols, traceability matrices, and summary reports. Support system handover to Operations, ensuring all punch-list items are resolved and systems meet operational and regulatory requirements. Provide leadership, guidance, and mentorship to junior C&Q engineers, fostering technical development and consistent execution standards. Support and oversee deviation management, change controls, CAPAs, and regulatory inspection readiness activities. Qualifications Degree in Engineering, Biotechnology, Pharmaceutical Sciences, or related discipline 10+ years’ experience in Commissioning & Qualification / CQV / Validation Strong working knowledge of GMP requirements, FDA and EMA regulations Strong hands-on upstream and downstream bioprocess knowledge Extensive experience working with Bioreactors, Filtration and concentration systems Excellent documentation, communication, and stakeholder engagement skills Other Requirements This is a site-based role. Must be able to commit to a minimum 40-hour work week, with flexibility based on project needs. Willingness to travel within Ireland and internationally , if required. Eligible to work full-time in Ireland. #J-18808-Ljbffr
A professional services company in Limerick is seeking a Senior IT Applications Analyst to manage the deployment and lifecycle of business-critical applications. You will collaborate with cross-functional teams to gather requirements, provide technical support, and ensure applications operate efficiently. Ideal candidates have a Bachelor’s degree in IT and at least 5 years of relevant experience. This role requires commitment to a 40-hour work week and the ability to travel to client sites as needed. #J-18808-Ljbffr
A global professional services company is seeking a Senior Validation Engineer in Dublin. This role involves leading validation activities, ensuring compliance with GMP standards, and managing project documentation. Candidates should have a bachelor's degree in engineering and 5–10 years of validation experience in the pharmaceutical industry. Strong problem-solving and communication skills are essential. #J-18808-Ljbffr
A professional services company in Dublin seeks a seasoned Validation Engineer to lead commissioning and validation activities for packaging lines. The ideal candidate will ensure compliance with GMP and regulatory standards, support cross-functional teams, and manage validation documentation. Required qualifications include a degree in Engineering and 5-10 years of validation experience in the Pharmaceutical or Life Sciences industry. #J-18808-Ljbffr
A leading company in the life sciences sector is seeking a CQV Engineer to join its growing operations in Ireland. The ideal candidate will oversee Commissioning, Qualification, and Validation activities while managing project documentation and ensuring safety compliance. Candidates should hold a relevant degree and have significant experience in life sciences processes, especially in Clean Utilities and Filling operations. This role offers an opportunity to work with cutting-edge technologies and contribute to lifesaving therapies. #J-18808-Ljbffr
