A global biotechnology company is seeking a Director of Cold Chain Management & GDP Compliance in Dublin. This hybrid role is critical for maintaining the integrity of temperature-sensitive pharmaceutical products and ensuring compliance with Good Distribution Practice regulations. The ideal candidate will have over 10 years of experience in supply chain management and strong leadership skills. Key responsibilities include overseeing cold chain systems, managing a global team, and ensuring regulatory compliance. Competitive compensation and a supportive work environment are offered. #J-18808-Ljbffr
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best — people with the right technical expertise and a relentless drive to solve real problems — and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well‑understood biology and provide an opportunity to be first‑to‑market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting‑edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Director Cold Chain Management & GDP Compliance Cork or Dublin - Hybrid role (2 days per week onsite) Closing Date: Friday 5th December 2025 Summary Description The Director, Cold Chain Management & Supply Chain GDP is a key role as part of the Global Distribution organisation. This role is critical to ensuring the integrity of temperature‑sensitive pharmaceutical products throughout the supply chain, while maintaining full compliance with Good Distribution Practice (GDP) regulations and internal quality standards. The incumbent will lead the Global Distribution Center of Excellence for cold chain engineering and Good Distribution Practices supporting distribution (storage and shipping) of all clinical and commercial materials in BioMarin. Responsibilities Cold Chain Engineering Lead the design, qualification and continuous improvement of cold chain systems and packaging solutions for temperature‑sensitive products. Oversee monitoring of temperature‑controlled logistics, including refrigerated transport, passive packaging and storage facilities. Collaborate with internal and external stakeholders to ensure robust cold chain solutions across global markets. Drive innovation in cold chain technologies and the streamlined management and quality of associated data. Supply Chain Compliance & GDP Ensure global compliance with GDP regulations and internal quality standards across all distribution channels. Develop and maintain policies, procedures and training programmes related to GDP and supply chain integrity. Primary point of contact in Supply Chain for audits and inspections related to distribution and cold chain operations. Partner with Quality, Regulatory and Logistics teams to proactively identify and mitigate compliance risks and bridge operational gaps. Leadership & Strategy Direct management of a team of individual contributors across global regions. Provide strategic direction and leadership to cross‑functional teams involved in cold chain and compliance activities. Advise senior leadership on investment decisions and emerging trends, providing timely risk insights and strategic recommendations that support informed decision‑making. SCOPE This role is responsible for supporting the efficient movement of lifesaving therapies in compliance with applicable regulations. Decisions made in this role are of critical nature in mitigating risks for the business while ensuring BioMarin's commercial products are delivered to patients in a timely and compliant manner. Candidate attributes A firm commitment to BioMarin's cultural beliefs and values. Consistent track record of exceeding objectives within area of influence. Ability to achieve results through others without direct reporting lines. Strong problem‑solving skills with a global focus both internally and externally. Possess a high level of accountability and demonstrate an ability to be a change agent in a highly regulated industry. Flexibility and ability to deal with changing priorities without losing sight of the overall business. Strong interpersonal, communication and influencing skills working with all levels and within an environment of constant change. Proactive and energetic outlook with an unwillingness to accept the status quo. Interaction and collaboration with team members, peers and senior management. Ability to work independently with strong time management skills. Education Bachelor's or Master's degree in Engineering, Supply Chain, Life Sciences or related field. 10+ years of experience in pharmaceutical supply chain, with significant expertise (minimum 5 years) in cold chain and GDP compliance. Proven leadership experience in a global, matrixed organisation. Strong knowledge of regulatory requirements (EU GDP, FDA, WHO, etc.). Excellent communication, stakeholder management and problem‑solving skills. Preferred Qualifications Experience with biologics, vaccines or advanced therapies. Familiarity with digital monitoring systems and data analytics in cold chain. Lean Six Sigma or similar process improvement certification. Experience Bachelor's degree in related curriculum with a minimum of 10-12 years of experience in global trade compliance. Previous experience leading a global team. Thorough understanding of technology tools, cold chain related systems and ERP systems, with a proven record of implementing scalable compliance solutions (systems, procedures and processes). Strong analytical and organisational skills with the ability to anticipate problems and take proactive actions to make the company's Trade Compliance stronger and more efficient. Proven ability to lead change initiatives and drive improvements within and across functions which enable compliance and mitigate risk. Ability to effectively work autonomously and independently. Circa 15% travel. Contacts Commercial, Site Operations, Clinical Supply Chain Operations, Worldwide Research & Development Scientists, Contract Manufacturing, Quality Assurance, Finance; External partners including 3PL providers, transport carriers. Equal Opportunity Employer / Other Note: This description is not intended to be all‑inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer / Veterans / Disabled. An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below. #J-18808-Ljbffr
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Director Cold Chain Management & GDP Compliance Cork or Dublin - Hybrid role (2 days per week onsite) Closing Date: Friday 5th December 2025 SUMMARY DESCRIPTION The Director, Cold Chain Management & Supply Chain GDP is a key role as part of the Global Distribution organisation. This role is critical to ensuring the integrity of temperature-sensitive pharmaceutical products throughout the supply chain, while maintaining full compliance with Good Distribution Practice (GDP) regulations and internal quality standards. The incumbent will lead the Global Distribution Center of Excellence for cold chain engineering and Good Distribution Practices supporting distribution (storage and shipping) of all clinical and commercial materials in BioMarin. RESPONSIBILITIES Cold Chain Engineering Lead the design, qualification, and continuous improvement of cold chain systems and packaging solutions for temperature-sensitive products. Oversee monitoring of temperature-controlled logistics, including refrigerated transport, passive packaging, and storage facilities. Collaborate with internal and external stakeholders to ensure robust cold chain solutions across global markets. Drive innovation in cold chain technologies and the streamlined management and quality of associated data. Supply Chain Compliance & GDP Ensure global compliance with GDP regulations and internal quality standards across all distribution channels. Develop and maintain policies, procedures, and training programs related to GDP and supply chain integrity. Primary point of contact in Supply Chain for audits and inspections related to distribution and cold chain operations. Partner with Quality, Regulatory, and Logistics teams to proactively identify and mitigate compliance risks and bridge operational gaps. Leadership & Strategy Direct management of a team of individual contributors across global regions Provide strategic direction and leadership to cross-functional teams involved in cold chain and compliance activities. Advise senior leadership on investment decisions and emerging trends, providing timely risk insights and strategic recommendations that support informed decision-making. SCOPEThis role is responsible for supporting the efficient movement of lifesaving therapies in compliance with applicable regulations. Decisions made in this role are of critical nature in mitigating risks for the business while ensuring BioMarin's commercial products are delivered to patients in a timely and compliant manner. The candidate should demonstrate the following attributes: A firm commitment to BioMarin's cultural beliefs and values Consistent track record of exceeding objectives within area of influence Ability to achieve results through others without direct reporting lines Strong problem-solving skills with a global focus both internally and externally Possess a high level of accountability and demonstrate an ability to be a change agent in a highly regulated industry Flexibility and ability to deal with changing priorities without losing sight of the overall business Strong interpersonal, communication and influencing skills working with all levels and within an environment of constant change Proactive and energetic outlook with an unwillingness to accept the status quo Interaction and collaboration with team members, peers and senior management Ability to work independently with strong time management skills EDUCATION Bachelor's or Master's degree in Engineering, Supply Chain, Life Sciences, or related field. 10+ years of experience in pharmaceutical supply chain, with significant expertise (minimum 5 years ) in cold chain and GDP compliance. Proven leadership experience in a global, matrixed organization. Strong knowledge of regulatory requirements (EU GDP, FDA, WHO, etc.). Excellent communication, stakeholder management, and problem-solving skills. Preferred Qualifications: Experience with biologics, vaccines, or advanced therapies. Familiarity with digital monitoring systems and data analytics in cold chain. Lean Six Sigma or similar process improvement certification. EXPERIENCEBachelor's degree in related curriculum with a minimum of 10-12 years of experience in global trade compliance Previous experience leading a global team Thorough understanding of technology tools, cold chain related systems and ERP systems, with a proven record of implementing scalable compliance solutions (systems, procedures, and processes). Strong analytical and organizational skills with the ability to anticipate problems and take proactive actions to make the company's Trade Compliance stronger and more efficient. Proven ability to lead change initiatives and drive improvements within and across functions which enable compliance and mitigate risk Ability to effectively work autonomously and independently Circa 15% travel CONTACTSCommercial, Site Operations, Clinical Supply Chain Operations, Worldwide Research & Development Scientists, Contract Manufacturing, Quality Assurance, Finance External partners including 3PL providers, transport carriers. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
Associate Director, Network Strategy - Cork Dublin Hybrid role Closing Date Friday 21st November 2025 Who We Are / Background BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. As we execute our corporate strategy and ensure we continue to supply products to patients at the right quality, service level and cost, how we configure our manufacturing network to meet these strategic objectives is critical to Technical Operations success. The Associate Director is a full-time member of the Network Strategy & Partnering team with accountability for leading strategic network analysis projects, feasibility options evaluations, and supporting other strategic initiatives with functions in BioMarin and throughout TOPS. This role offers a unique opportunity to shape the future of BioMarin's global manufacturing network. The successful candidate will be at the forefront of strategic decision-making, leveraging cutting-edge analytics to drive innovation and operational excellence. RESPONSIBILITIES Business process owner for Network Strategy assessments, overseeing and coordinating the process from intake, review, analysis to decision Execute specific network analysis actions (eg. CMO selection, Make v Buy) which come out of our modality and network strategies, by building rigorous analyses that synthesize insight into actionable recommendations. Cross functional partnership with Manufacturing, TDS, Quality & Supply chain teams to ensure timely decision making on product / node decisions to support long term patient demand and delivery of product development milestones Own and support the development of network strategy analytical tools and models including maintenance of accurate and up to date data sets to reflect current long term assumptions on demand and capacity Lead the development and application of advanced analytical tools, including stochastic modeling techniques, to simulate network scenarios under demand uncertainty. Use probabilistic frameworks to inform strategic decisions and optimize manufacturing configurations across modalities. Analyze business opportunities and challenges within the TOPS organization. Provide financial and strategic analyses of decision options and make recommendations to senior management. Craft compelling narratives and business cases that translate complex analyses into clear, actionable recommendations. Effectively communicate insights to senior leadership, shaping strategic decisions through data-driven articulation of a recommended future state. Lead project teams and influence overall strategic thinking. Proactively manage teams and work with stakeholders to define and implement strategic initiatives; Responsible for successful, on-time project completion and achieved results. Do an excellent job of partnering with stakeholders to prepare and present analyses, decisions and recommendations to senior management. Translate the operations strategy into sound delivery options. Responsible for performing options analysis and developing high level feasibility project necessary, create turn over documentation and assure smooth transition from planning to project implementation Ownership and accountability to keep key network strategy documents current such as; network strategy / assessment docket of work, quarterly value tracker, process and best practice documentation, decision log Ownership and accountability for development and maintenance of Business Development Playbooks to support TOPS BD Integration plans and needs Stay current in external trends and best practices. EXPERIENCE Desired Skills & Expectations: 8-10 years work experience in pharmaceutical /biopharmaceutical; 2-5 years in decision support roles. Must work well in a collaborative team environment and communicate effectively with customers, peers, and senior management. Strong influence and interpersonal skills, and the ability to work well with others in a proactive, positive, and constructive manner. Excellent communications skills: Oral, written and formal presentation skills with senior management, middle management and line staff with aptitude for creating presentations, graphs and charts to concisely convey relevant data, trends, etc. Proven ability to influence senior stakeholders through persuasive storytelling, supported by rigorous analysis and well-structured business cases. Skilled in synthesizing technical and financial data into executive-level presentations that drive alignment and action. Agility in coordinating with teams virtually across multiple international geographic locations. Analytical model development, use and maintenance to support complex decision making Creative problem solving skills with the ability to exercise high levels of resourcefulness in seeking information Strategic agility and strong attention to detail and execution Comfortable and effective working indirectly through others Demonstrated project management skills and proven ability to translate developed business strategy into tangible implementation options. Chemical/Biological engineering / science or background and direct experience in manufacturing and international experience preferred. Ability to work with little supervision: meet deadlines, prioritize assignments, provide recommendations, and effectively communicate updates. Demonstrated self-motivator and proactive in managing long-term or on-going projects in balance with daily routine. Ability to manage and handle sensitive financial information relating to project cost reports, facilities planning, etc. Proven ability to manage multiple, fast moving priorities. EDUCATION Bachelors in Engineering, Science, Business, Operations Management, or Industrial Engineering required, Master's Degree preferred (particularly MBA).Other advanced degree with strong focus on operations, supply chain, finance, quantitative methods, or operations research. Other continuing education initiatives is highly desirable (e.g. People Management, Leadership Six Sigma, Lean Manufacturing, APICS certification, industry specific coursework) Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Packaging Operations Team Lead - 12 Month Assignment Closing date: 30th November 2025 BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind. All Packaging Technicians and Shift Leads from respective shifts will report to the Packaging Operations Team Lead. Packaging Operations Team Lead will be responsible for people management of these direct reports including development, coaching, appraisals and performance management. Reporting to the Packaging Operations Manager, the primary role of the Packaging Operations Team Lead is to manage the daily packaging operations; coordinating resources, establishing priorities, being point of escalation for the team and ensuring schedule and deadlines are met. Packaging Operations Team Lead will lead the team through successful product launch activities, process validation and regulatory inspections. It is expected the Packaging Operations Team Lead will develop a high-performing, team based organization, where colleagues are flexible, multi-skilled and empowered to make decisions that result in safe, agile and compliant packaging of Finished goods. A high level of initiative, energy and motivation are key role requirements, as well as organizationaland people management skills. Main areas of responsibility: People management of direct reports of packaging technicians and shift Lead and support the packaging team to ensure delivery of the production schedule. Assist in troubleshooting and facilitate appropriate Support and partner closely with the Packaging BPS, Warehouse, Quality (QA & QC), Engineering and other colleagues. Represent the Packaging group as necessary at critical meetings (e.g. Daily Ops meeting, S&OE, Functional Lead Team meeting etc.) Responsible for reporting out on key performance indicators (e.g. Schedule adherence, Changeover performance, Unplanned downtime etc.) Develop and demonstrate an active approach to safety, industrial hygiene, environmental and regulatory compliance Responsible for ensuring training records and training plans are in place and up to date for all team members. Ensure training, master batch records, SOPs and other documents are current and compliant under cGMP. Lead and support daily operation of processing systems and partner with plant engineering colleagues to ensure equipment is reliably maintained and within appropriate calibration. Partner with validation subject matter experts, prepare/approve validation protocols, validation plans, protocol executions, and summary reports in support of ongoing revalidation and validation efforts required for commercial manufacturing. Instill the use of Right First Time (six-sigma) and lean manufacturing practices leading to operational excellence. Coach, mentor and train shift leads and packaging technicians on packaging processes, use of operational excellence tools, and high-performance team behaviors. Assist in preparation of performance evaluations and coaching of staff. Assist in the recruitment and hiring process for the Packaging operations team. Participate and support plant optimization that helps create a strong value propositionfor future investment. (Including input into current capital projects) Required to worked closely with the Packaging project lead to support the delivery of the Packaging strategic master plan. Strong focus of visibility boards for packaging metrics and status with particular focus on schedule adherence & changeover performance EDUCATION Degree in science/engineering, operations management or industrial engineering or equivalent experience in a GMP environment is preferred. EXPERIENCE Past experience and demonstrated ability to successfully influence team performance in a high-performance team is strongly preferred. Track record of embedding a strong Quality culture, Trackwise experience preferred. Demonstrate strong communication skills and the ability to interact across cross-functional teams. Demonstrated ability to train and coach colleagues in processing, operational excellence, team interactions and delivering results. Experience with regulatory inspections and direct interaction with regulatory inspectors. Highly developed organizational and leadership skills. Process development and/or technology transfer experience preferred. CONTACTS Work closely with QA Operations, Packaging Development, Engineering , Material Operations & Packaging technicians & BPS's to support escalation resolution and implement effective CAPA's. SUPERVISOR RESPONSIBILITY The Packaging Operations Team Lead of a given functional area will typically have ~8-15 direct reports; Packaging technicians and shift leads. The Packaging Operations Team Lead will be responsible for a group of ~8-15 staff including a full rotating 2 shift Operations shift pattern. (Early & lates Monday to Friday). The role may require the successful candidate to work shift operations that align with the business needs. Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind. BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients' lives. BioMarin Electrical and Instrumentation Apprenticeship4 year Apprenticeship ProgramShanbally, Ringaskiddy, Cork SUMMARY BioMarin has a high-performing, team based organization, where colleagues are flexible, multi-skilled and empowered to make decisions. A high level of initiative, energy and motivation are key role requirements, as well as excellent organizational skills. The Apprentice Electrical & Instrumentation Technician will serve as an integral member of the Maintenance and Engineering team in an end-to-end (Drug Substance, Drug Product and Packaging) manufacturing facility. The successful candidate will be able to demonstrate a high standard of work, adhere to schedules and be a good communicator with strong interpersonal skills. The successful candidate will also have good self-awareness, act decisively and be a complete team player. If successful the candidate must attend block releases through a number of phases throughout the 4 year apprenticeship program. This may require attendance to one of the various technical institutions while maintaining and keeping the FAS / Solas register up to date. RESPONSIBILITIES Provide support to the on-site maintenance and engineering personnel in daily routine and non-routine tasks. Operate and maintain electrical systems such as electrical distribution networks, emergency standby equipment, utilities and HVAC. Opportunity to provide technical support to various cross functional teams throughout the site. Responsible for providing support to all electrical and calibration/instrumentation equipment so they remain operational, available for use and ensure it is GxP compliant at all times. Ensure that all maintenance & calibration duties are carried out in accordance to cGMP regulations, safety considerations and site quality standards. Use of permit to work system and other on-site safety systems to control engineering activities. EDUCATION Applicants must have achieved at least Grade D in five Leaving Certificate subjects, including Mathematics, English and preferably one Technical/Science subject. (Current leaving cert students may apply but offer is subject to successfully pass these subjects). Why choose an apprenticeship with BioMarin? Achieve a nationally recognised qualification while working Get paid a competitive salary whilst working towards a qualification - earn while you learn! Learn from experienced mentors in a world-class biopharma environment Build valuable skills and career prospects in a growing industry Additional Information: In order to be considered for this apprenticeship, you will need to be legally authorised to work in Ireland for the duration of the program. To apply, please submit your CV and Cover Letter. This program will commence in Autumn 2026. Note: This description is not intended to be all-inclusive or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
Who We Are BioMarin is a global biotechnology company that relentlessly pursues bold science to translate genetic discoveries into new medicines that advance the future of human health. Since our founding in 1997, we have applied our scientific expertise in understanding the underlying causes of genetic conditions to create transformative medicines, using a number of treatment modalities. Using our unparalleled expertise in genetics and molecular biology, we develop medicines for patients with significant unmet medical need. We enlist the best of the best - people with the right technical expertise and a relentless drive to solve real problems - and create an environment that empowers our teams to pursue bold, innovative science. With this distinctive approach to drug discovery, we've produced a diverse pipeline of commercial, clinical and preclinical candidates that have well-understood biology and provide an opportunity to be first-to-market or offer a substantial benefit over existing therapeutic options. About Technical Operations BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Manufacturing Engineering Apprentice Shanbally, Ringaskiddy, Cork This 3-year program which will commence in Autumn 2026 combines workplace learning onsite with BioMarin in Shanbally, Ringaskiddy, with academic studies at Munster Technological University (MTU), leading to a Level 7 Bachelor of Engineering in Manufacturing Engineering. This is an exciting opportunity to be part of the BioMarin Engineering team and work in a fast-paced, collaborative, and supportive environment where learning, growth and development is endless. Throughout your apprenticeship a senior member of the Capital Projects Engineering team will be your mentor, providing guidance and development opportunities throughout your journey with BioMarin. This apprenticeship was designed with close alignment to the current needs of the Irish manufacturing industry therefore providing invaluable experience to the apprentice and increasing BioMarin's pipeline of STEM2D (Science, Technology, Engineering, Maths, Manufacturing and Design) talent. On successful completion, the Manufacturing Engineering Apprentice will be awarded with a Bachelor of Engineering in Manufacturing Engineering (Apprenticeship), Level 7. Who can apply? Applicants that have achieved at least Grade 06 in 5 Leaving Certificate subjects, including Mathematics, English and preferably one Technical / Science subject with a minimum of 250 CAO points is required. Applications also open to those completing their Leaving Certificate in June 2026. Key Responsibilities The Manufacturing Engineering Apprentice will report to a Senior Member of Capital Projects team, during your 3--year apprenticeship , and will participate in design, procurement, construction and commissioning of Pharmaceutical Production Processes, Facilities and Utility systems. BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These individuals build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Learn how to develop and execute the design, engineering, and commissioning of new systems. Learn how to provide technical support to the Engineering Department on the specification of pharmaceutical equipment, systems, and new facilities. Learn how to support develop and integrate complex civil, mechanical, electrical and process systems in a pharmaceutical environment. Learn how to prepare SOPs, Functional Specifications, Detailed Design Specifications, Engineering Drawings and other documents required for a cGMP pharmaceutical environment. Participate in quality and compliance initiatives. Develop and review training materials. Other duties as assigned. What awaits you at BioMarin? This is a fantastic opportunity to work with a leading-edge Biopharmaceutical company who, through focusing on genetic diseases, gives its employees the opportunity to truly impact and transform patient's lives. Over two decades ago when we first opened our doors, we focused on giving much-needed attention to the underserved communities of those with rare diseases. These rare disease communities mostly affected children and were often ignored. At the time, BioMarin developed the only treatments for these life-altering conditions, giving hope to patients and families. Competitive salary with annual increases (Earn while you learn!) Onsite gym Free car parking Subsidised canteen Note: This description is not intended to be all-inclusive, or a limitation of the duties of the position. It is intended to describe the general nature of the job that may include other duties as assumed or assigned. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
Senior Director, Head of External Operations, Global External Operations (GEO) Dublin or Cork (Hybrid role 2 days per week onsite) with travel within US, Japan and Europe at 25%. BioMarin is the world leader in delivering therapeutics that provide meaningful advances to patients who live with serious and life-threatening rare genetic diseases. We target diseases that lack effective therapies and affect relatively small numbers of patients, many of whom are children. These conditions are often inherited, difficult to diagnose, progressively debilitating and have few, if any, treatment options. BioMarin will continue to focus on advancing therapies that are the first or best of their kind. BioMarin's Technical Operations group is responsible for creating our drugs for use in clinical trials and for scaling production of those drugs for the commercial market. These engineers, technicians, scientists and support staff build and maintain BioMarin's cutting-edge manufacturing processes and sites, provide quality assurance and quality control to ensure we meet regulatory standards, and procure the needed goods and services to support manufacturing and coordinating the worldwide movement of our drugs to patients. Come join our team and make a meaningful impact on patients' lives. The role of Snr. Director, Head of External Operations, GEO will provide leadership for all manufacturing and packaging operations which take place in Contract Manufacturing locations globally to support BioMarin's clinical pipeline and commercial product portfolio. The core focus of the role is to ensure timely delivery of quality commercial and clinical product to support patient supply from our CMO network. Our CMO operations span multiple sites (approx. 20) and multiple technology platforms namely, Biologic Drug Substance, Synthetic Drug Substance, Oral Solid Dose, Sterile Drug Product, Combination Products, and Packaging. The successful candidate will provide leadership to a global team of Managers with responsibility for operational management and oversight of the CMOs and other key suppliers within the BioMarin network. The position reports directly to the Vice President of Global External Operations. The successful candidate will be tasked with leading the implementation, standardisation, and enhancement of a number of global Process Teams consisting of cross functional representation with members from QA, Supply Chain, MSAT, Operations, and other key functions. These cross functional teams have accountability to deliver approved commercial product from our global network of Clinical and Commercial CMOs to support over $2bn of revenue across 8 commercial products with significant planned future growth. Additionally, this role will have accountability for the delivery of released product to support our exciting clinical pipeline (e.g., Make-Assess-Release and Ready - Run - Release processes). The Snr. Director, Head of External Operations will be a member of the GEO Leadership Team (GEO Leadership Team) where they will have shared accountability for managing the global external supply business, setting our vision and developing and delivering our strategic roadmap. This role will also be a key member of other governance bodies within TOPS and across BioMarin. Primary Activities: Ensure delivery of quality product on time from our CMO network to support clinical and commercial supply plans, proactively resolving issues that escalate from Process Teams (Make - Assess - Release and Ready - Run - Release processes). Partner with MSAT, External Quality, and Partner Management team to oversee & support product launch programs, tech transfers, technical changes, labelling updates, etc. Manage the trades offs & risks between longer-term strategic programs & day-to-day supply activities. Develop the Operations model supporting the teams as they look to standardise work, eliminate waste and focus on cross functional working relationships to ensure product supply. Recruit, onboard, & train operations professionals to ensure the team has the appropriate experience & capabilities to provide oversight across the E2E pharmaceutical value chain. Manage career development & succession planning for external operations teams. Manage CMO performance and develop the CMO relationship through routine cycle of Business Review Meetings (BRMs), Quality Review Meetings (QRM), and Joint Steering Committee (JSCs) Meetings as well as ad hoc visits as needed. Lead our strategic roadmap to deliver against agreed targets (eg. lead time reduction, cost reduction, metrics enhancements). Partner with Quality, Site Supply Chain, MSAT, and others to develop cross functional goals to drive continuous improvement (Quality, Cost, Delivery, Customer Service) in CMO Operations. Represent CMO Operations in the Sales and Operations Planning process. Lead development and management of CMO Operations budget and long-range plan (approx. $200m+ annual spend). Support the CMO selection process by evaluating CMO capabilities against applicable manufacturing, quality and compliance requirements and needs of BioMarin - both operational capabilities & strategic objectives. Support development of strategic partnerships with CMOs. Partner with Compliance, Legal and Procurement teams to negotiate Master Supply Agreements with beneficial terms for BioMarin. Proactively manage and communicate operational risks across the CMO network and develop mitigation plans in partnership with other functional leaders. Develop risk-based strategies for the CMO operations oversight, considering the product life cycle, complexity and CMO capabilities. Develop CMO Operations team to ensure BioMarin continues to attract, retain, and engages key talent. Qualifications/Experience: Bachelor's degree in a Life Sciences, Chemistry, Chemical Engineering or Pharmaceutical Engineering discipline required. Minimum of 15 years of relevant biotechnology or pharmaceutical industry experience within operations, quality, or supply chain. 10+ years of direct experience in a GMP manufacturing environment and 7+ years of team leadership. Direct and broad experience in GMP manufacturing across multiple platforms (biologics; synthetics; oral dose; parenteral manufacturing; packaging). Experience overseeing multiple product launch / NPI / Tech Transfer programs. Experience with regulatory agency inspections (e.g., FDA, TGA). Previous experience leading global teams in multiple locations. Strong leadership track record and experience in operations management with CMOs or internal operations. Demonstrated ability to hire, coach and grow leadership talent. Experience in developing, implementing and leading a cross functional operations model. Strong focus and passion for Operational Excellence and Continuous improvement. Track record of delivery on operational improvements across Quality, Cost, Delivery and Customer Service. Strong leadership track record especially in the areas of leading in a global and matrix environment, working cross functionally and developing talent. Excellent written and verbal communication skills at all levels in the organization. Experience managing department budget / spend. Role is remote with travel to HQ in San Rafael California up to 6 times per year. Ability to travel to CMOs up to 25-50%, when required. Equal Opportunity Employer/Veterans/Disabled An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
Who We Are For more than two decades, going our own way has led to countless breakthroughs, bettering the lives of those suffering from rare genetic disease. In 1997 we were founded to make a big difference in small patient populations. Now we seek to make an even greater impact by applying the same science-driven, patient-forward approach that propelled our last 25 years of drug development to larger genetic disorders, as well as genetic subsets of more common conditions. Through our unparalleled expertise in genetics and molecular biology, we will continue to develop targeted therapies that address the root cause of the conditions we seek to treat. Applying our knowledge to make a transformative impact is not just a calling, but an obligation to those who will benefit most. The end goal has always been better lives and now we can reach more. And the more people we reach, the more our impact can grow. We transform lives through genetic discovery Our Culture Our desire to make a positive impact on our patients extends to our employees and BioMarin is committed to fostering an inclusive environment where every person feels seen, valued, and heard - so employees can thrive in all areas of their lives, in and outside of work. We seek to provide an open, flexible, and friendly work environment to empower people and to provide them with the ability to develop their long-term careers. Ultimately, we want to be an organization where people enjoy coming to work and take pride in our efforts to help patients. By providing a foundation for all operations company wide, BioMarin's General and Administrative teams support our mission of providing first and best in class therapeutics to patients who live with rare diseases. Our teams include groups such as finance, legal, human resources, corporate compliance and ethics, and information technology. Come join our team and make a meaningful impact on patients' lives. Tax Manager/ Senior Manager Cork/ Dublin (hybrid) 12 Month Contract Role Summary The taxteam is seeking a highly talented and motivated Tax Manager/Senior Manager to support the direct tax compliance and provisioning process for up to 25 entities in the EMEA region The ideal candidate will have previous corporate tax experience in a multinational/Big 4 environment who is looking to get broader experience in a dynamic, fast-paced environment. Responsibilities Managequarterly and yearly current and deferred tax provisions for group reportingunder US GAAP and annual statutory disclosures under IFRS for multiple group companies. This would include the preparation and review of workings,working with the EMEA and GlobalTax and Finance teamsas well as dealing with financial auditors and local advisors as required. Partner with the widerFinance teams on thestatutory account preparation process Work with and manage external service providers as required in order to meet our corporate tax and withholding tax compliance and payment obligations across each jurisdiction with the assistance of the Senior Tax Analyst Manage the R&D tax credit process including preparing calculations, identifying and working with the appropriate internal teams and liaising with external advisors Work closely with the Treasury team to ensure appropriate funding and hedging in place for upcoming tax payments as well as working with the team on proposed investment strategies Develop and maintain strong relationships with internal stakeholders as well as external tax advisors and local tax authorities Work closely with Legal, Finance and the wider business to provide commercially focused and actionable guidance, advice and support ontax related matters Assist the EMEA and Global Tax Teams with tax projects such as tax system implementation/automation and the identification and implementation of continuous improvement initiatives Support the Tax Director and Global Tax team on tax planning strategies and opportunities Keep up to date with legislative developments and ensuring the implications of all legislative changes are addressed appropriately Support and managetax audits/enquiries as they arise This role will also incorporate some other tasks in the tax department such as preparing and maintaining process documentation, maintaining compliance and risk trackers and supplier engagement and fee management Other duties as assigned. EducationRequired Irish Tax Institute qualified/Qualified accountant (ACA, ACCA or CIMA) Undergraduate Degree in Business, Finance, or Accounting Experience Required Minimum 6years Corporate Tax experience, preferably in a multinational environment. Proficient in Microsoft office especially Outlook/Excel/Word/Power BI etc. ERP experience, ideally Oracle/SAP Experience with data analytics tools/tax software an advantage Strong attention to detail, analytical skills & initiative with the ability to adhere to strict timelines Able to work well as part of a team and influence cross functional groups as well as proven ability to develop effective working relationships Experience in managing and mentoring Ability to embrace change and be flexible to changing business needs Self-motivated and results orientated strategic thinker with solid business understanding Strong interpersonal, written, and oral communication skills 1 To be considered for this role you will be redirected to and must complete the application process on our careers page. To start the process click the Continue to Application or Login/Register to apply button below.
